Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance
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چکیده
منابع مشابه
Inhibitory effects of Cheonggukjang extracts on radiation-induced micronucleus formation and inflammasome activation
Background: People are exposed to more radiation than before with the application of radiation technology. Radiation is known to induce damage to cell structure, DNA, chromosomes and nucleus. In this study, we showed that CGJ extract can inhibit radiation-induced chromosomal damage in vivo and NLRP7 inflammasome activation in vitro, suggesting that the compound from CGJ can Be considered as a t...
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Serine hydrolases are a large family of multifunctional enzymes known to influence obesity. Here, we performed activity-based protein profiling to assess the functional level of serine hydrolases in liver biopsies from lean and obese humans in order to gain mechanistic insight into the pathophysiology of metabolic disease. We identified reduced hepatic activity of carboxylesterase 2 (CES2) and ...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2017
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-17-0351